Desloratadine is a tricyclic H1-antihistamine is an active metabolite of Loratadine.
Desloratadine is a selective H1-antihistamine which functions as an inverse agonist at the histamine H1 receptor.
It is also an antagonist at all subtypes of the muscarinic acetylcholine receptors.
It exhibits only peripheral activity since it does not readily cross the blood-brain barrier; hence, it does not cause drowsiness because it does not readily enter the central nervous system.
It has a long-lasting effect and is effective in moderate and low doses.
Desalert useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine
Contraindication: Desloratadine is contraindicated in patients who have shown a previous hypersensitivity to it.
Storage Instructions :
Store in a cool dry place. Protect from moisture and light.