Hyperpigmentation is a concentrated and usually localized increase in the skin’s natural colour. These dark spots are mainly located on the face, neckline and back of the hands and are usually harmless
WHAT CAUSES HYPERPIGMENTATION?
Skin’s natural colour is due to the pigment melanin produced by melanocytes, the cells present in the skin. Hyperpigmentation is due to over production of melanin by melanocytes. This over production is mainly caused by UV light exposure which induces inflammation, oxidative stress and DNA damage in keratinocytes. As a result, mediators are released which causes excessive melanin production by stimulation of melanocytes and melanin is deposited in keratinocytes to protect the skin from over exposure causing solar lentigines or seasonal spots called Freckles.
Other causes of hyperpigmentation are enviromental factors like Smoke: Cigarette, Auto Emission and Factory Smoke, Hormonal changes (Melasma)such as those in Aging, Pregnancy, Birth Control Pills, Post-menopausal Hormone Replacement Therapy and Post-inflammatory hyperpigmentation in acne prone skin.
NEED TO CONTROL
- Exposure to UV Rays
- Melanin deposition in cells
- Melanin production
- Oxidant and Inflammatory activity